Protein Dynamical Mapping for Allosteric Drug Targeting
An instrument and method for identification of potential allosteric sites through the measurement of a protein's long-range vibrations.
Background:
Conventional approaches for drug design are largely focused on exploiting sites where other molecules are known to bind (i.e. active sites). Because a protein’s active site can possess...
Published: 12/1/2020
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Inventor(s): Andrea Markelz, Katherine Niessen, Gheorghe Acbas
Keywords(s): Technologies
Category(s): Technology Classifications > Instrumentation, Technology Classifications > Optics and Photonics, Campus > University at Buffalo
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