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Stable Micelle Drug Formulations

Researchers at The University at Buffalo have developed a novel method that is effective in formulating drugs. Hydrophobic drug formation traditionally requires heavy use of surfactants for administration. This technology, which is available for licensing, produces concentrated hydrophobic drugs that produce fewer negative side effects than traditional...
Published: 11/18/2020   |   Inventor(s): Jonathan Lovell, Wentao Song, Yumiao Zhang
Keywords(s): Technologies
Category(s): Technology Classifications > Dental > Diagnostics, Technology Classifications > Drug Delivery, Technology Classifications > Nanotechnology, Campus > University at Buffalo

Polar Coding for Noisy Write-Once Memories (Cal Tech lead)

Write-once memory is a model for data-storage devices, where a set of binary cells are used to store data, and the cell levels can only increase when the data is rewritten. The WOM model was recently identified as a good model for flash memories, where rewriting delays expensive block erasures and by that leads to better preservation of cell quality...
Published: 11/18/2020   |   Inventor(s): Michael Langberg (UB Inventor), Eyal En Gad(non-UB), Yue Li(non-UB), Jehoshua Bruck (non-UB), Joerg Kliewer (non-UB), Anxiao Jiang
Keywords(s): Technologies
Category(s): Technology Classifications > Dental > Diagnostics, Technology Classifications > Healthcare, Technology Classifications > Computers, Campus > University at Buffalo

Small Molecule Imaging of Fungi by PET Scanning

Isotopically-labeled calcofluor derivatives to differentiate fungal lung infections from bacterial or cancer nodules in immunosuppressed patients by PET scanning. This relates to the field of radioactive, isotopically-labeled calcofluor derivatives and uses of such to detect fungi, such as filamentous fungi including Aspergillus species, such as by...
Published: 11/18/2020   |   Inventor(s): John Panepinto, Peter Williamson (non-UB), Dale Kiesewetter (non-UB), Jin Qiu (non-UB)
Keywords(s): Technologies
Category(s): Technology Classifications > Dental > Diagnostics, Technology Classifications > Research Tools and Reagents, Campus > University at Buffalo

A Novel Marker for Detection of Prostate Cancer

Myosine IC isoform A is overexpressed in prostate cancer tissues and metastatic cells. The monoclonal antibodies and PCR tools developed here detect overexpression. In 2012 a novel isoform of myosine IC designated isoform A was discovered. Several years later tissue distribution studies discovered it was overexpressed in prostate cancer tissues and...
Published: 11/18/2020   |   Inventor(s): Wilma Hofmann
Keywords(s): Technologies
Category(s): Technology Classifications > Dental > Diagnostics, Technology Classifications > Healthcare, Campus > University at Buffalo

Nanoformulated Tetrapyrroles as Biophotonic Contrast Agents

Researchers at The University at Buffalo have developed a unique method to prepare GI tract imaging contrast agents. This innovation is a breakthrough for GI tract imaging and can be used to effectively treat patients. The patented method can be used to prepare optical imaging contrast dye that is not readily absorbed by the GI tract. It achieves this...
Published: 11/18/2020   |   Inventor(s): Jonathan Lovell, Chulhong Kim, Yumiao Zhang, Mansik Jeon
Keywords(s): Technologies
Category(s): Technology Classifications > Imaging, Technology Classifications > Healthcare, Technology Classifications > Dental > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Materials and Chemicals, Campus > University at Buffalo

Detecting a Bacterial Process in Chronic Rhinosinusitis

By looking for bacterial markers this assay distinguishes the various forms of Chronic Rhinosinusitis for quicker and more accurate clinical treatments. Chronic Rhinosinusitis (CRS) is an inflammatory disease involving the sinuses and nasal cavity which effects 32 million in the US. Differentiation between chronic and acute sinusitis would allow for...
Published: 11/18/2020   |   Inventor(s): Jens Ponikau, Hirohito Kita, David Sherris
Keywords(s): Featured, Technologies
Category(s): Technology Classifications > Screens and Assays, Technology Classifications > Dental > Diagnostics, Campus > University at Buffalo

Monoclonal Antibody 3F5-5E5 and P107 Diagnostic Markers and Putative Vaccine Antigen for Moraxella Catarrhalis and Supplemental Mab 4G5

Monoclonal antibodies, proteins, nucleic acid sequences and lipoologosaccharides specific to Moraxella catarrhalis. These materials are useful for designing a much-needed diagnostic test. This invention includes monoclonal antibodies, proteins, nucleic acid seqeunces and lipoologosaccharides (LOS) which are specific to Moraxella catarrhalis. These...
Published: 11/18/2020   |   Inventor(s): Anthony Campagnari, Kristin Furano, Amy Howlett, Nicole Luke- Marshall
Keywords(s): Technologies
Category(s): Technology Classifications > Dental > Diagnostics, Technology Classifications > Research Tools and Reagents, Campus > University at Buffalo

PCR primers that specifically identify Moraxella catarrhallis

PCR-based test to diagnose Moraxella Catarrhalis (MC) by amplifying a region of the MC chromosome and clone genes in serotype A, B & C. M. Catarrhalis is a significant cause of human respiratory diseases and in particular is a major cause of otitis media in young children. The invention consists of PCR Primers that demonstrate quick and definitive...
Published: 11/18/2020   |   Inventor(s): Anthony Campagnari, Katie Edwards, Nicole Luke- Marshall
Keywords(s): Technologies
Category(s): Technology Classifications > Dental > Diagnostics, Campus > University at Buffalo

Neural Network for Predicting Respiratory Disturbance Index

The invention is an artificial neural network that can predict the respiratory disturbance index of patients suspected of sleep apnea syndrome. An artificial neural network is a numerical processor that accepts multiple features simultaneously, usually in digital form about a series of individual cases. Artificial neural networks have a propensity for...
Published: 11/18/2020   |   Inventor(s): Brydon J. Grant (Deceased), Ali EL-Solh
Keywords(s): Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Dental > Diagnostics, Technology Classifications > Healthcare, Campus > University at Buffalo

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