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Monoclonal Antibody 3F5-5E5 and P107 Diagnostic Markers and Putative Vaccine Antigen for Moraxella Catarrhalis and Supplemental Mab 4G5

Monoclonal antibodies, proteins, nucleic acid sequences and lipoologosaccharides specific to Moraxella catarrhalis. These materials are useful for designing a much-needed diagnostic test. This invention includes monoclonal antibodies, proteins, nucleic acid seqeunces and lipoologosaccharides (LOS) which are specific to Moraxella catarrhalis. These...
Published: 11/18/2020   |   Inventor(s): Anthony Campagnari, Kristin Furano, Amy Howlett, Nicole Luke- Marshall
Keywords(s): Technologies
Category(s): Technology Classifications > Dental > Diagnostics, Technology Classifications > Research Tools and Reagents, Campus > University at Buffalo

PCR primers that specifically identify Moraxella catarrhallis

PCR-based test to diagnose Moraxella Catarrhalis (MC) by amplifying a region of the MC chromosome and clone genes in serotype A, B & C. M. Catarrhalis is a significant cause of human respiratory diseases and in particular is a major cause of otitis media in young children. The invention consists of PCR Primers that demonstrate quick and definitive...
Published: 11/18/2020   |   Inventor(s): Anthony Campagnari, Katie Edwards, Nicole Luke- Marshall
Keywords(s): Technologies
Category(s): Technology Classifications > Dental > Diagnostics, Campus > University at Buffalo

Outer Membrane Protein B1 of Moraxella Catarrhalis

The present invention includes a method for the isolation and purification of outer membrane protein B1 as well as B1 peptides from Moraxella catarrhalis, and the resulting compositions. The method involves growing the bacteria in iron-depleted medium to enhance the expression of the B1 protein, harvesting the bacteria from the culture, extracting from...
Published: 11/18/2020   |   Inventor(s): Anthony Campagnari
Keywords(s): Technologies
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > University at Buffalo

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